Alzheimer's is a devastating
disorder of the brain's nerve cells that impairs memory, thinking, and
behavior and leads, ultimately, to death. The impact of Alzheimer's on
individuals, families and our health care system makes the disease one
of our nation's greatest medical, social and fiscal challenges. An estimated
6.5 Million Americans have Alzheimer's and the figure is estimated to touch
15 Million by 2020 as baby boomers age. Increasing age is the greatest
risk factor for Alzheimer's. One in 10 individuals over 60 and nearly half
of those over 80 are affected. Inherited forms of Alzheimer's disease can
strike individuals as early as their 30s and 40s. It could cost as
much as $70,000 per year towards nursing cost( at present cost levels).
Family members are forced to pay most of it from their packet as there
is no meaningful insurance cover for Alzheimer's. Apart from the medical
cost there is a huge maintenance cost. After the onset of Alzheimer's the
patient can be expected to live anything from 8 years to 20 years.
The average maintenance cost at present rates could be anything from $200,000
upwards for his full time.
The silver lining is that finding
a treatment that could delay onset could reduce the number of individuals
with Alzheimer's disease by nearly 50 percent.
In this context certain herbal combination
Shilajit and Withania Somnifera show surprising results on Alzheimer's
patients. They have been found to boost memory and enhance cognition in
Alzheimer's patients. Shilajit is a mineral pitch found in Himalayan mountains
and Withania Somnifera also known as Indian ginseng is a herb found in
India. Withania somnifera has proven memory boosting effects and is also
known to boost stamina.
Systemic administration of
Shilajit & Withania Somnifera combination for enhancing cognition in
Alzheimer's patients
Following is the details of research done by Scientists
Schliebs R.; Liebmann A.; Bhattacharya S.K.; Kumar
A.; Ghosal S.; Bigl V. and R. Schliebs
at Paul Flechsig Institute Brain Res., Department of Neurochemistry,
University of Leipzig, D-04109 Leipzig, Germany.
" Although some promising results
have been achieved by acetyl cholinesterase inhibitors, an effective therapeutic
intervention in Alzheimer's disease still remains an important goal. Sitoindosides
VII-X, and withaferin-A, isolated from aqueous methanol extract from the
roots of cultivated, varieties of Withania somnifera (known as Indian
Ginseng - ASHWAGANDHA ), as well as SHILAJIT, a
pale-brown to blackish brown exudation from steep rocks of the Himalayan
mountain, are used in Indian medicine to attenuate cerebral functional
deficits, including amnesia, in geriatric patients. The present investigation
was conducted to assess whether the memory enhancing effects of plant extracts
from Withania somnifera and Shilajit are owing to neurochemical alterations
of specific transmitter systems. Therefore, histochemistry to analyze acetyl
cholinesterase activity as well as receptor auto radiography to detect
cholinergic, glutamatergic and GABAergic receptor subtypes were performed
in brain slices from adult male Wistar rats, injected intraperitoneally
daily with an equimolar mixture of sitoindosides VII-X and withaferin-A
(prepared from Withania somnifera) or with Shilajit, at doses of 40 mg/kg
of body weight for 7 days.
Administration of Shilajit led
to reduced acetyl cholinesterase staining, restricted to the basal forebrain
nuclei including medial septum and the vertical limb of the diagonal band.
Systemic application of the defined
extract from Withania somnifera, however, led to differential effects on
AChE activity in basal forebrain nuclei: slightly enhanced AChE activity
was found in the lateral septum and globus pallidus, whereas in the vertical
diagonal band AChE activity was reduced following treatment with sitoindosides
VII-X and withaferin-A. These changes were accompanied by enhanced M1-muscarinic
cholinergic receptor binding in lateral and medial septum as well as
in frontal cortices, whereas the M2-muscarinic receptor binding sites were
increased in a number of cortical regions including cingulate, frontal,
piriform, parietal acid retrosplenial cortex.
Treatment with Shilajit or the defined
extract from Withania somnifera affected neither GABA(A) and benzodiazepine
receptor binding nor NMDA and AMPA glutamate receptor subtypes in any of
the cortical or sub cortical regions studied.
The data suggest that Shilajit
and the defined extract from Withania somnifera affect preferentially events
in the cortical and basal forebrain cholinergic signal transduction cascade.
The drug induced increase in cortical
muscarinic Acetylcholine receptor capacity might partly explain the cognition
enhancing and memory improving effects of extracts from Withania
somnifera observed in animals and humans.
Contact Details at
Department of Neurochemistry, University of Leipzig
Paul Flechsig Institute of Brain Research
Department of Neurochemistry
Jahnallee 59
04109 Leipzig
GERMANY
Director: Prof. Dr. Volker Bigl
Fon: +49 (0) 341 97 25 701
Fax: +49 (0) 21 14 492
|
Order
Shilajit & Withania Somnifera
|
Shilajit &
Withania
Somnifera Combination- 4 Months Supply
If
any of your near or dear one is afflicted by Alzheimer's we strongly recommend
Shilajit & Withania Somnifera combination. This will boost the quality
of life and ease the burden. The mails and phone calls we get in this regard
thanking us gives immense happiness to us.
As
such anyone can take this combination for it's memory and stamina boosting
effects. Shilajit (Fulvic acid) is a known antiaging elixir. Shilajit and
Withania Somnifera combination serve as a powerful nervine &
cerebral tonic fortifying brain cells against degeneration. This combination
can surely prevent the onset of any brain degenerative disease like Alzheimer's
, Parkinson's, dementia etc.
This
combination has been proven to be very effective in preventing, arresting
and reversing Alzheimer's and Parkinson's conditions.
4 Packets of
Shilajit & 4 Bottles of Withania Somnifera- 4 Months Course
– U.S.$84.95 ( includes free Shipping worldwide)
 U.S.$
84.95 (
Free shipping worldwide)
|
